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Lab disinfectants on ZAGENO

RNase AWAY™ Surface Decontaminant Thermo Scientific
Disinfectant Types Surfactant Applicable Processes Decontamination, Removal of RNase Quantity /
From $ 54.20 (475 ml)
Sizes 4 (475 - 5000 ml)
Catalog IDs 7002PK, 7003PK, ...
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Diethyl pyrocarbonate, ≥97% (NMR) Sigma-Aldrich
Disinfectant Types Cleansing Applicable Processes Disinfection, Removal of RNase Quantity 5 ml, 25 ml, 50 ml, 100 ml
From $ 57.10 (5 ml)
Sizes 4 (5 - 100 ml)
Catalog IDs D5758-5ML, D5758-25ML, ...
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Contec™ Sporicidin™ Disinfectant Wipes Contec
Disinfectant Types Cleansing Applicable Processes Disinfection Quantity 510 wipes (85/canister) (9.5 x 12 in./24.1 x 30.5cm), 2160 Wipes (180/canister) (5 x 8 in./12.7 x 20.3cm)
From $ 218.79 (2160 Wipes)
Sizes 2 (510 - 2160 Wipes)
Catalog IDs JUM8506F, CAN18012F
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Betadine Solution - 16oz ACE
Disinfectant Types / Applicable Processes / Quantity /
From $ 7.79 (473 ml)
Sizes 1 (473 ml)
Catalog IDs 733-2105
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GELPLATE-CLEAN™ G-Biosciences
Disinfectant Types Cleansing Applicable Processes Cleaning Quantity 500 ml, 1000 ml, 2000 ml
From $ 45.00 (500 ml)
Sizes 4 (500 - 2000 ml)
Catalog IDs 786-140, 786-140RF-I, ...
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WASH (Wash Solution), 10 L Beckman Coulter
Disinfectant Types / Applicable Processes / Quantity /
From $ 170.00 (10 l)
Sizes 1 (10 l)
Catalog IDs 447060
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Radiacwash AliMed
Disinfectant Types / Applicable Processes / Quantity /
From $ 28.00 (1 Gallon)
Sizes 1 (1 Gallon)
Catalog IDs 937658
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DCN 90 solution Sigma-Aldrich
Disinfectant Types Cleansing Applicable Processes Cleaning Quantity 5000 ml
From $ 130.50 (5000 ml)
Sizes 1 (5000 ml)
Catalog IDs 30472
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RNaseOUT™ G-Biosciences
Disinfectant Types Cleansing Applicable Processes Cleaning, Removal of RNase Quantity 250 ml, 1000 ml
From $ 35.00 (250 ml)
Sizes 2 (250 - 1000 ml)
Catalog IDs 786-70, 786-71
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VIRKON S DISINFECTANT 10LB W/DYE Pharmacal Research Laboratories
Disinfectant Types Oxidizing agents, Surfactant Applicable Processes Disinfection Quantity 4536 g
From $ 93.47 (4536 g)
Sizes 1 (4536 g)
Catalog IDs 03010F
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ElectroZap™ Electrode Decontamination Solution Ambion
Disinfectant Types Surfactant Applicable Processes Decontamination Quantity 250 ml
From $ 68.75 (250 ml)
Sizes 1 (250 ml)
Catalog IDs AM9785
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Aldon™ Laboratory Cleaner Fisher Scientific
Disinfectant Types Cleansing Applicable Processes Cleaning Quantity 118 ml, 946 ml
From $ 3.95 (118 ml)
Sizes 2 (118 - 946 ml)
Catalog IDs S20714, S20715
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Alcohol

Several types of alcohol are known to be effective disinfectants against microorganisms, but the most commonly used alcohols in the laboratory are ethanol and isopropanol. Although alcohol can act rapidly against microorganisms (vegetative bacteria, viruses, and fungi) with a broad antimicrobial activity, it should be noted that alcohol is unable to kill many spores and some of the non-lipid viruses. Therefore, it is not recommended to use alcohol for the disinfection and sterilization of medical devices.

To achieve the highest effectiveness, the concentration of disinfectant alcohol solution should be least 70 % (v/v). Though little is known about the specific mode of action of alcohol against microorganisms, it is believed that the membrane and proteins are degraded upon exposure to alcohol, leading to cell lysis.

Hydrogen peroxide

Hydrogen peroxide (H2O2) is another disinfectant that is widely used for decontamination. Hydrogen peroxide is an oxidant that can produce hydroxyl free radicals which can attack vital components of cells such as DNA, lipids, and proteins.

Commercially available hydrogen peroxide can be purchased in a colorless liquid form. Compared with alcohol, hydrogen peroxide shows a broader antimicrobial activity spectrum due to its action on bacterial spores. Furthermore, when compared with other disinfectants hydrogen peroxide is somewhat more environmentally friendly since it degrades contaminants to water and hydrogen, which are non-toxic to the environment.

For disinfection, hydrogen peroxide is always used at a concentration between 3 % to 6 %. However, higher concentration (10-30 %) and longer time of exposure are required for the elimination of bacterial spores. It is also worth noting that the catalase and peroxidase activities of microorganisms can affect their tolerance to hydrogen peroxide.

Chlorine

Chlorine is a highly active oxidizing agent that can be used as a disinfectant. Chlorine used for disinfection purposes is always sold in the form of sodium hypochlorite (household bleach, NaOCl). NaOCl always needs to be diluted to 1:10 before use. When microorganisms are exposed to chlorine or chlorine-based agents, chlorine will penetrate their outer layer and destroy the structure and activity of the cellular proteins by denaturing them resulting in microbial death.

Formaldehyde

Formaldehyde, also known as methanal, is a highly active, water-soluble chemical (Formalin) and can react with DNA, RNA, and proteins. As formaldehyde can penetrate the outer layer of spores, it is widely used for disinfection and sterilization in hospitals. Formaldehyde can also be used for preserving/fixing tissues or cells as formaldehyde is capable of forming crosslinks between proteins. Despite the high activity and efficiency of formaldehyde as a disinfectant, care should be taken due to its carcinogenic properties.

Problems in the lab? Learn about methods and experiments in our Knowledge section or look up a specific Troubleshooting guide.