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Lab disinfectants on ZAGENO

Softcide Hand Wash SKU : 21016-06-001 Thermo Scientific
From $ 14.78 (1 Unit)
Sizes 2 (1 - 6 Unit)
Catalog IDs 21016-06-001-1, 21016-06-001-6
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DECON-CYCLE VAI
From $ 293.29 (12 Units)
Sizes 1 (12 Units)
Catalog IDs DCY-06-16Z-01
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PREempt™ Concentrate Disinfectant SKU: 21311 Connecticut Cleanroom
From $ 2,561.40 (1 Unit)
Sizes 1 (1 Unit)
Catalog IDs 21311
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PREempt™ RTU Disinfectant Solution and Wipes SKU: 21101 Connecticut Cleanroom
From $ 171.29 (12 Units)
Sizes 1 (12 Units)
Catalog IDs 21101
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Thomas Clean-Wipes SKU: 2061 CONTROL COMPANY
From $ 12.75 (1 Unit)
Sizes 1 (1 Unit)
Catalog IDs 2061
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LABX® 123 Wipers SKU: LB123.1212.30 Berkshire
From $ 957.64 (15000 Units)
Sizes 1 (15000 Units)
Catalog IDs LB123.1212.30
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LABX® 170 Wipers SKU: LB170.0909.40 Berkshire
From $ 847.96 (20000 Units)
Sizes 1 (20000 Units)
Catalog IDs LB170.0909.40
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LENSX® 90 SKU: LN90.0406.24 Berkshire
From $ 391.70 (24000 Units)
Sizes 1 (24000 Units)
Catalog IDs LN90.0406.24
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MICROFIRST® Wipers SKU: MF.0909.20 Berkshire
From $ 620.67 (6000 Units)
Sizes 1 (6000 Units)
Catalog IDs MF.0909.20
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MICROFIRST® Wipers SKU: MF.1212.20 Berkshire
From $ 626.58 (3000 Units)
Sizes 1 (3000 Units)
Catalog IDs MF.1212.20
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MICROSEAL® 1200 Wipers SKU: MS1200.1212.6 Berkshire
From $ 431.64 (800 Units)
Sizes 1 (800 Units)
Catalog IDs MS1200.1212.6
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POLX® 1200 Wipers SKU: P1200.0909.8 Berkshire
From $ 328.98 (1200 Units)
Sizes 1 (1200 Units)
Catalog IDs P1200.0909.8
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Alcohol

Several types of alcohol are known to be effective disinfectants against microorganisms, but the most commonly used alcohols in the laboratory are ethanol and isopropanol. Although alcohol can act rapidly against microorganisms (vegetative bacteria, viruses, and fungi) with a broad antimicrobial activity, it should be noted that alcohol is unable to kill many spores and some of the non-lipid viruses. Therefore, it is not recommended to use alcohol for the disinfection and sterilization of medical devices.

To achieve the highest effectiveness, the concentration of disinfectant alcohol solution should be least 70 % (v/v). Though little is known about the specific mode of action of alcohol against microorganisms, it is believed that the membrane and proteins are degraded upon exposure to alcohol, leading to cell lysis.

Hydrogen peroxide

Hydrogen peroxide (H2O2) is another disinfectant that is widely used for decontamination. Hydrogen peroxide is an oxidant that can produce hydroxyl free radicals which can attack vital components of cells such as DNA, lipids, and proteins.

Commercially available hydrogen peroxide can be purchased in a colorless liquid form. Compared with alcohol, hydrogen peroxide shows a broader antimicrobial activity spectrum due to its action on bacterial spores. Furthermore, when compared with other disinfectants hydrogen peroxide is somewhat more environmentally friendly since it degrades contaminants to water and hydrogen, which are non-toxic to the environment.

For disinfection, hydrogen peroxide is always used at a concentration between 3 % to 6 %. However, higher concentration (10-30 %) and longer time of exposure are required for the elimination of bacterial spores. It is also worth noting that the catalase and peroxidase activities of microorganisms can affect their tolerance to hydrogen peroxide.

Chlorine

Chlorine is a highly active oxidizing agent that can be used as a disinfectant. Chlorine used for disinfection purposes is always sold in the form of sodium hypochlorite (household bleach, NaOCl). NaOCl always needs to be diluted to 1:10 before use. When microorganisms are exposed to chlorine or chlorine-based agents, chlorine will penetrate their outer layer and destroy the structure and activity of the cellular proteins by denaturing them resulting in microbial death.

Formaldehyde

Formaldehyde, also known as methanal, is a highly active, water-soluble chemical (Formalin) and can react with DNA, RNA, and proteins. As formaldehyde can penetrate the outer layer of spores, it is widely used for disinfection and sterilization in hospitals. Formaldehyde can also be used for preserving/fixing tissues or cells as formaldehyde is capable of forming crosslinks between proteins. Despite the high activity and efficiency of formaldehyde as a disinfectant, care should be taken due to its carcinogenic properties.

Problems in the lab? Learn about methods and experiments in our Knowledge section or look up a specific Troubleshooting guide.