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Growth Factors
Human IL-25, research grade SKU: 130-115
Activity
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Purity
/
/
Applicable Processes
/
/
Scientific Score
9.65
Brand
Miltenyi Biotec
Sizes
2 (5 - 25 µg)
Available From
1 Vendor
Price Range
$ 70.00 - $ 230.00
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Growth Factors
Human Interleukin-8 (hIL-8) #94853
Activity
/
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Purity
/
/
Applicable Processes
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Scientific Score
9.26
Brand
Cell Signaling Technology
Sizes
1 (25 µg)
Available From
1 Vendor
Price
$ 228.00
Catalog IDs
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Growth Factors
Recombinant Hu Visfatin (Cf) 25 Ug
Scientific Score
0.49
Brand
Tonbo Biosciences
Sizes
1 (25 µg)
Available From
1 Vendor
Price
$ 193.97
Catalog IDs
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Growth Factors
Recombinant Hu Pdgf-Bb (Cf) 10 Ug
Scientific Score
0.49
Brand
Tonbo Biosciences
Sizes
1 (10 µg)
Available From
1 Vendor
Price
$ 129.90
Catalog IDs
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Growth Factors
Epidermal Growth Factor (EGF), mouse natural (culture grade), 100 µg SKU: 356001
Activity
/
/
Purity
>95% by SDS-PAGE and >80% by pH 9.9 PAGE
>95% by SDS-PAGE and >80% by pH 9.9 PAGE
Applicable Processes
Cell culture
Cell culture
Scientific Score
8.04
Brand
Corning
Sizes
1 (1000 µg)
Available From
2 Vendors
Price Range
$ 1,038.28 - $ 1,384.31
Catalog IDs
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Growth Factors
MethoCult™ M3134 SKU: 03134
Activity
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Purity
/
/
Applicable Processes
/
/
Scientific Score
8.36
Brand
STEMCELL Technologies
Sizes
1 (40 ml)
Available From
1 Vendor
Price
$ 80.00
Catalog IDs
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Growth Factors
Sodium Butyrate SKU: 72242
Activity
/
/
Purity
≥ 95%
≥ 95%
Applicable Processes
/
/
Scientific Score
8.45
Brand
STEMCELL Technologies
Sizes
1 (500 mg)
Available From
1 Vendor
Price
$ 54.00
Catalog IDs
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Growth Factors
StemSpan™ SFEM II
Activity
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/
Purity
/
/
Applicable Processes
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/
Scientific Score
8.18
Brand
STEMCELL Technologies
Sizes
2 (100 - 500 ml)
Available From
1 Vendor
Price Range
$ 123.00 - $ 418.00
Catalog IDs
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Growth Factors
Pyrintegrin
Activity
/
/
Purity
≥ 95%
≥ 95%
Applicable Processes
/
/
Scientific Score
9.65
Brand
STEMCELL Technologies
Sizes
2 (1 - 10 mg)
Available From
1 Vendor
Price Range
$ 163.00 - $ 316.00
Catalog IDs
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Growth Factors
Recombinant Human GMFB
Scientific Score
4.48
Brand
Applied Biological Materials
Sizes
3 (10 - 1000 µg)
Available From
1 Vendor
Price Range
$ 70.00 - $ 1,690.00
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Growth Factors
Recombinant Human IL18
Scientific Score
4.44
Brand
Applied Biological Materials
Sizes
3 (25 - 1000 µg)
Available From
1 Vendor
Price Range
$ 70.00 - $ 2,520.00
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Growth Factors
Recombinant Human LTA
Scientific Score
3.41
Brand
Applied Biological Materials
Sizes
3 (20 - 1000 µg)
Available From
1 Vendor
Price Range
$ 70.00 - $ 1,250.00
Added to comparison remove item

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Growth Factor Function

Growth factors act as signaling molecules between cells. The signaling may occur between local cells (paracrine signaling), between distant cells (endocrine signaling) or the same cell that produced the signal binds its “own” growth factor (autocrine signaling). To induce the signal cascade, growth factors bind to their specific receptor situated on the cell membrane or, in the case of the fat-soluble steroid hormones, inside of the cell. Growth factors often target receptors of the tyrosine kinase family followed by downstream signaling transduction pathways like the MAP kinase signaling cascade.

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Growth Factor Stimulation

Growth factors are important for the regulation of many different cellular processes. Usually, they are naturally occurring proteins or steroid hormones and are capable of stimulating:

• cell growth

• proliferation

• tissue repair

• cellular differentiation

• cell survival

• inflammation

There are many different growth factors which are often grouped into families like the Transforming Growth Factor (TGF) family or the family of Interleukins (IL).

Applications In Vivo and In Vitro

In vivo, many cells require the presence of different growth factors to proliferate or differentiate and to maintain their viability. In in vitro cell cultures, some cell lines require the addition of growth factors to the culture medium in order to proliferate. Additionally, they could be used to stimulate differentiation of cell lines.

In the clinic, growth factors may be utilized in the treatment of different diseases. For example, neutropenia may be treated with hematopoietic growth factors (granulocyte-colony stimulating factor (G-CSF)).

Available growth factors are often produced by genetic engineering. Therefore, recombinant bacteria, which have the particular genes inserted and are able to transcribe these genes as well as to translate the mRNA into the corresponding proteins, are produced. After protein extraction and purification, the growth factors are ready to be used in your experiments.