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Fixatives

Score 7.50

Hartman’s Fixative SKU : h0290

Sigma-Aldrich

From
$ 111.00 (500 ml)
Sizes
1 (500 ml)
Catalog IDs
H0290-500ML
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Fixatives

Score 9.14

Glutaraldehyde solution SKU : 340855

Sigma-Aldrich

Format
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From
$ 40.25 (25 ml)
Sizes
2 (1 - 25 L)
Catalog IDs
340855-1L, 340855-25ML
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Fixatives

Score 7.41

Formalin Free Tissue Fixative SKU : a5472

Sigma-Aldrich

From
$ 89.24 (1 gal)
Sizes
1 (1 gal)
Catalog IDs
A5472-1GAL
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Fixatives

Score 9.66

Formaldehyde solution SKU : 47608

Sigma-Aldrich

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From
$ 70.87 (250 ml)
Sizes
2 (250 - 1000 ml)
Catalog IDs
47608-250ML-F, 47608-1L-F
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Fixatives

Score 3.66

Scigen™ Mercury Free Buffered Zinc Fixatives, SKU: 5043

Scigen

From
$ 145.31 (19 L)
Sizes
1 (19 L)
Catalog IDs
5043
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Fixatives

Score 3.51

Modified Davidson's Fixative II, SKU: 518755

RICCA

From
$ 1,230.36 (1 Unit)
Sizes
1 (1 Unit)
Catalog IDs
518755
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Fixatives

Score 3.51

Scigen™ VIP-Fixative™ Non-Precipitating 10% NBF, SKU: 5991

Scigen

From
$ 145.45 (19 L)
Sizes
1 (19 L)
Catalog IDs
5991
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Fixatives

Score 3.51

Bouin's Fixative, SKU: K227A

MichClone

From
$ 1,357.00 (4320 ml)
Sizes
1 (4320 ml)
Catalog IDs
K227A
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Fixatives

Score 6.53

Ultraffin™ Ultra-Purified Histology Paraffin Wax, SKU: EEPAR2B

Pro Lab Diagnostics

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From
$ 130.73 (18 lb)
Sizes
1 (18 lb)
Catalog IDs
EEPAR2B
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Fixatives

Score 6.53

Dynamic Diagnostics TransPak™ Pre-filled 10% Neutral Buffered Formalin (NBF), SKU: MA0102013

Dynamic Diagnostics

Format
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From
$ 239.00 (1 Case)
Sizes
1 (1 Case)
Catalog IDs
MA0102013
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Fixatives

Score 6.83

Dynamic Diagnostics TransPak™ Pre-filled 10% Neutral Buffered Formalin (NBF), SKU: MA0102014

Dynamic Diagnostics

Format
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From
$ 159.99 (1 Case)
Sizes
1 (1 Case)
Catalog IDs
MA0102014
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Fixatives

Score 1.23

Azer Scientific Pre-Filled 10% Neutral Buffered Formalin, SKU: BPFNBF120

Azer Scientific

From
$ 166.10 (1 Case)
Sizes
1 (1 Case)
Catalog IDs
BPFNBF120
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Fixative Applications

Fixation is a crucial step in the preparation of histological sections. By terminating ongoing biochemical reactions, fixatives kill tissues and prevent post-mortem decay, enabling fresh biological tissues to be preserved in a state as close to natural as possible. Fixatives disable biomolecules, such as proteolytic enzymes that would normally digest and damage the sample. Also, through their toxicity and unpalatability to micro-organisms, fixatives protect the sample from external damage.

Irrespective of how carefully a fixative is applied, the process of fixation always alters the sample by introducing artifacts that interfere with the interpretation of the slide. Artifacts vary according to tissue type and processing technique, so when deciding on your exact methodology, be sure to take artifacts into account and select techniques that minimize their appearance.

A range of different fixatives are available, including the two most common: formaldehyde and glutaraldehyde.

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