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Brand
Sigma-Aldrich
Sizes
1 (1 gal)
Available From
2 Vendors
Price Range
$ 89.24 - $ 99.00
Catalog IDs
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Formaldehyde solution for molecular biology, 36.5-38% in H2O
Format
/
Composition
/
Applicable Processes
/
Scientific Score
9.40
Brand
Sigma-Aldrich
Sizes
3 (25 - 500 ml)
Available From
2 Vendors
Price Range
$ 24.51 - $ 46.30
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Formaldehyde-DNPH solution SKU : crm47177
Format
/
Composition
/
Applicable Processes
/
Scientific Score
7.16
Brand
Supelco
Sizes
1 (1 ml)
Available From
1 Vendor
Price
$ 37.46
Catalog IDs
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Fixing solution SKU : f7264
Format
/
Composition
/
Applicable Processes
/
Scientific Score
8.58
Brand
Sigma-Aldrich
Sizes
2 (1 - 500 L)
Available From
2 Vendors
Price Range
$ 174.00 - $ 492.07
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Brand
Sigma-Aldrich
Sizes
1 (4 L)
Available From
2 Vendors
Price Range
$ 44.85 - $ 49.80
Catalog IDs
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Brand
Sigma-Aldrich
Sizes
2 (4 - 19 L)
Available From
2 Vendors
Price Range
$ 44.39 - $ 160.00
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Glutaraldehyde solution SKU : g6257
Format
/
Composition
/
Applicable Processes
/
Scientific Score
8.92
Brand
Sigma-Aldrich
Sizes
2 (100 ml)
Available From
2 Vendors
Price Range
$ 29.74 - $ 36.20
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Glutaraldehyde solution SKU : g7651
Format
/
Composition
/
Applicable Processes
/
Scientific Score
9.31
Brand
Sigma-Aldrich
Sizes
2 (10 - 100 ml)
Available From
2 Vendors
Price Range
$ 68.20 - $ 343.41
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Hartman’s Fixative SKU : h0290
Scientific Score
7.50
Brand
Sigma-Aldrich
Sizes
1 (500 ml)
Available From
2 Vendors
Price Range
$ 114.00 - $ 168.58
Catalog IDs
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Brand
Sigma-Aldrich
Sizes
2 (1 - 100 L)
Available From
2 Vendors
Price Range
$ 51.02 - $ 178.00
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Formalin solution, neutral buffered, 10% SKU : HT5014
Format
/
Composition
/
Applicable Processes
/
Scientific Score
8.97
Brand
Sigma-Aldrich
Sizes
1 (1 Case)
Available From
1 Vendor
Price
$ 80.25
Catalog IDs
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Formalin solution, neutral buffered, 10% SKU : HT5012
Format
/
Composition
/
Applicable Processes
/
Scientific Score
9.87
Brand
Sigma-Aldrich
Sizes
1 (1 Case)
Available From
1 Vendor
Price
$ 80.25
Catalog IDs
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Fixative Applications

Fixation is a crucial step in the preparation of histological sections. By terminating ongoing biochemical reactions, fixatives kill tissues and prevent post-mortem decay, enabling fresh biological tissues to be preserved in a state as close to natural as possible. Fixatives disable biomolecules, such as proteolytic enzymes that would normally digest and damage the sample. Also, through their toxicity and unpalatability to micro-organisms, fixatives protect the sample from external damage.

Irrespective of how carefully a fixative is applied, the process of fixation always alters the sample by introducing artifacts that interfere with the interpretation of the slide. Artifacts vary according to tissue type and processing technique, so when deciding on your exact methodology, be sure to take artifacts into account and select techniques that minimize their appearance.

A range of different fixatives are available, including the two most common: formaldehyde and glutaraldehyde.

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