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DNA & RNA Extraction Kits

Score 3.17

quickAmp™ Tissue PCR Kit

ACTGene

From
$ 192.03 (100 Reactions)
Sizes
2 (100 - 1000 Reactions)
Catalog IDs
A1500-100RXN, A1500-1000RXN
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DNA & RNA Extraction Kits

Score 5.50

Blood Mini QC

A&A Biotechnology / oneservice

Targets
Genomic DNA
Genomic DNA
Sample Type
Blood, Body fluids
Blood, Body fluids
Time to Sample
/
/
From
$ 36.00 (12 Preparations)
Sizes
3 (12 - 240 Preparations)
Catalog IDs
OOS-AA-022-QC-D, OOS-AA-022-48QC, ...
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DNA & RNA Extraction Kits

Score 8.16

E.Z.N.A.® Gel Extraction Kit, Q-Spin

Omega Bio-tek

From
$ 62.00 (50 Tests)
Sizes
2 (50 - 200 Tests)
Catalog IDs
D2501-01, D2501-02
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DNA & RNA Extraction Kits

Score 2.98

Column-Pure Bacterial Genomic DNA Isolation Kit

Applied Biological Materials

From
$ 195.00 (50 Preparations)
Sizes
1 (50 Preparations)
Catalog IDs
D511
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DNA & RNA Extraction Kits

Score 5.40

Diffinity RapidTip® SKU : d1947

Sigma-Aldrich

From
$ 26.00 (8 Reactions)
Sizes
1 (8 Reactions)
Catalog IDs
D1947-8RXN
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DNA & RNA Extraction Kits

Score 5.46

Diffinity RapidTip®2 SKU : d2947

Sigma-Aldrich

From
$ 23.60 (8 Reactions)
Sizes
2 (8 - 48 Reactions)
Catalog IDs
D2947-8RXN, D2947-48RXN
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DNA & RNA Extraction Kits

Score 2.80

innuSPEED Bacteria/Fungi DNA Kit

Analytik Jena

From
$ 244.99 (50 Reactions)
Sizes
2 (50 - 250 Reactions)
Catalog IDs
845-KS-1510050, 845-KS-1510250
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DNA & RNA Extraction Kits

Score 2.38

innuSPEED Soil DNA Kit

Analytik Jena

Targets
/
/
Sample Type
/
/
Time to Sample
/
/
From
$ 244.99 (50 Reactions)
Sizes
1 (50 Reactions)
Catalog IDs
845-KS-1580050
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DNA & RNA Extraction Kits

Score 3.16

Lysing Matrix E, 2mL Tubes

MP Biomedicals

From
$ 215.41 (50 Tubes)
Sizes
3 (50 - 500 Tubes)
Catalog IDs
116914050, 116914100, ...
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DNA & RNA Extraction Kits

Score 4.49

AxyPrep™ Mag Plasmid Kit

AXYGEN

Targets
/
/
Sample Type
/
/
Time to Sample
/
/
From
$ 731.92 (1 Kit)
Sizes
1 (1 Kit)
Catalog IDs
MAG-P-M
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DNA & RNA Extraction Kits

Score 5.15

NUCLEOBOND XTRA MIDI 50 PREPS

Macherey-Nagel

From
$ 552.09 (1 Kits)
Sizes
1 (1 Kits)
Catalog IDs
12363348
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DNA & RNA Extraction Kits

Score 6.07

Macherey-Nagel™ NucleoBond™ PC EF Kit, 2,000 EF

Macherey-Nagel

Targets
Plasmid DNA
Plasmid DNA
Sample Type
Culture
Culture
Time to Sample
150 min
150 min
From
$ 412.36 (5 Reactions)
Sizes
1 (5 Reactions)
Catalog IDs
740549
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DNA & RNA Extraction Function & Applications

DNA Extraction and RNA extraction are key to acquiring deoxyribonucleic acid / ribonucleic acid from cell or virus samples. It is important to know that purification, extraction, and isolation interchangeable terms but can refer to slightly different processes. Purification usually relates to eliminating contaminants, while isolation is removing as much of the target as physically possible. Extraction can combine both of these terms or be similar to isolation.

DNA extraction is vital to the downstream processes of PCR, sequencing, and genotyping, while RNA extraction is key for gene expression studies, gene knockdown, gene silencing processes and transcriptome analysis. However, isolating RNA is a meticulous process due to the presence of RNases within cells. These enzymes require inhibiting as they can rapidly degrade RNA and reduce the overall yield.

Both DNA & RNA extraction are vital first steps for preparing the final sample.

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DNA Extraction

DNA Purification, which commonly uses magnetic beads or silica columns, requires these steps:

• Cell lysis via the use of:
* Chaotropic Salts – make it possible for DNA to bind to solid phase (e.g. silica membrane)
* Detergents – able to degrade proteins and cellular structures, including the nuclear envelope
* Enzymes – such as proteinase K and RNases, which break down proteins and RNA respectively

• Removal of contaminants (e.g. carbohydrates) through centrifugation and pipetting, specific methods include:
* Ethanol Precipitation – DNA is insoluble in alcohol
* Phenol-Chloroform Extraction – Phenol removes proteins in the aqueous layer
* Mini-column / Spin Column Purification – DNA will bind to silica under the correct conditions

Check out our article about the Coral Reefs and DNA extraction tips for working with this sample type.

RNA Extraction

RNA Purification, in general, runs as follows:

  • Guanidine thiocyanate and a reducing agent disrupt the cells

  • Vigorous shaking or vortexing break any disulfide bonds as well as inactivating any contaminants

  • Phenol and chloroform-isoamyl, followed by centrifugation, separate RNA in the cell

  • Ethanol washing (75%) removes impurities from the precipitate.

Compare RNA Extraction Kits!

With our compare function, you can avoid all the time and energy wasted sifting through multiple web pages from different suppliers. At ZAGENO you can clearly see kits side-by-side, with the relevant attributes for each kit neatly in line for easy selection of the best product for you.

The ZAGENO comparison does not highlight one kit to be better than the other, as the kit of choice may vary between
researchers - depending on each individual's preferred attributes. The best kit is the one that meets your needs - ZAGENO allows
you to make an informed decision with minimum effort.

Check out our How It Works page for a guide to using the comparison function.

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Videos:

MrSimpleScience/YouTube

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