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High Pure PCR Cleanup Micro Kit
Input Type
Gel, PCR reaction
Gel, PCR reaction
Targets
Genomic DNA, cDNA
Genomic DNA, cDNA
Removal
Dimers, Salts, Small molecules, Unincorporated nucleotides, Unincorporated primers
Dimers, Salts, Small molecules, Unincorporated nucleotides, Unincorporated primers
Scientific Score
8.84
Brand
Roche Life Science
Sizes
2 (50 - 200 Reactions)
Available From
1 Supplier
Price Range
$ 120.00 - $ 412.00
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Oligo Clean-Up and Concentration Kit
Input Type
Enzymatic reaction
Enzymatic reaction
Targets
Oligonucleotides
Oligonucleotides
Removal
/
Scientific Score
8.35
Brand
Norgen Biotek
Sizes
1 (50 Reactions)
Available From
1 Supplier
Price
$ 233.00
Catalog IDs
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ChIP Elute Kit
Input Type
Other sources
Other sources
Targets
Genomic DNA, Proteins
Genomic DNA, Proteins
Removal
/
Scientific Score
7.53
Brand
TaKaRa
Sizes
1 (50 Reactions)
Available From
1 Supplier
Price
$ 399.00
Catalog IDs
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GenElute™ PCR Clean-Up Kit
Input Type
PCR reaction
PCR reaction
Targets
Genomic DNA
Genomic DNA
Removal
Enzymes, Salts, Unincorporated nucleotides, Unincorporated primers
Enzymes, Salts, Unincorporated nucleotides, Unincorporated primers
Scientific Score
9.85
Brand
Sigma-Aldrich
Sizes
1 (70 Reactions)
Available From
2 Suppliers
Price Range
$ 121.60 - $ 130.00
Catalog IDs
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GET™ AGAROSE DNA
Input Type
Gel
Gel
Targets
Genomic DNA, Plasmid DNA
Genomic DNA, Plasmid DNA
Removal
/
Scientific Score
8.43
Brand
G-Biosciences
Sizes
2 (50 - 100 Reactions)
Available From
2 Suppliers
Price Range
$ 78.00 - $ 130.00
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NucleoSpin® 8 PCR Clean-up Core Kit
Input Type
PCR reaction
PCR reaction
Targets
Genomic DNA
Genomic DNA
Removal
Dimers, Unincorporated primers
Dimers, Unincorporated primers
Scientific Score
9.12
Brand
Macherey-Nagel
Sizes
1 (384 Reactions)
Available From
1 Supplier
Price
$ 670.00
Catalog IDs
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NucleoSpin® 8 / 96 PCR Clean-up Core Kit
Input Type
PCR reaction
PCR reaction
Targets
Genomic DNA
Genomic DNA
Removal
Dimers, Proteins, Salts, Unincorporated primers
Dimers, Proteins, Salts, Unincorporated primers
Scientific Score
9.27
Brand
Macherey-Nagel
Sizes
1 (384 Reactions)
Available From
1 Supplier
Price
$ 670.00
Catalog IDs
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NucleoBond® BAC 100
Input Type
/
Targets
Plasmid DNA
Plasmid DNA
Removal
/
Scientific Score
9.17
Brand
Macherey-Nagel
Sizes
1 (10 Reactions)
Available From
1 Supplier
Price
$ 294.00
Catalog IDs
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CelLytic™ PN Isolation/Extraction Kit SKU : cellytpn1
Input Type
/
Targets
/
Removal
/
Scientific Score
4.61
Brand
Sigma-Aldrich
Sizes
1 (1 Kit)
Available From
2 Suppliers
Price Range
$ 457.00 - $ 501.61
Catalog IDs
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GenElute™ 96 Well PCR Clean-Up Kit
Input Type
PCR reaction
PCR reaction
Targets
Genomic DNA
Genomic DNA
Removal
Dimers, Enzymes, Salts, Unincorporated nucleotides, Unincorporated primers
Dimers, Enzymes, Salts, Unincorporated nucleotides, Unincorporated primers
Scientific Score
9.42
Brand
Sigma-Aldrich
Sizes
1 (384 Reactions)
Available From
2 Suppliers
Price Range
$ 763.00 - $ 771.00
Catalog IDs
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Pur-A-Lyzer™ Maxi Dialysis Kit SKU : PURX35050
Input Type
/
Targets
/
Removal
/
Scientific Score
5.63
Brand
Sigma-Aldrich
Sizes
1 (50 Units)
Available From
1 Supplier
Price
$ 309.00
Catalog IDs
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CelLytic™ Y Plus Kit SKU : cyp1
Input Type
/
Targets
/
Removal
/
Scientific Score
4.61
Brand
Sigma-Aldrich
Sizes
1 (1 Kit)
Available From
2 Suppliers
Price Range
$ 605.00 - $ 664.74
Catalog IDs
Added to comparison remove item

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Cleanup kits have become a vital part of extracting proteins or nucleic acids, as chances are you will need to remove some impurities before you start your experiments. That's where cleanup kits come in. Cleanup kits helps you remove impurities carried over from the purification processes, in preparation for downstream applications.

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Your Perfect Solution - Millions of Products - Expert Advice

Protein cleanup

For protein biochemistry, cleanup kits are used to prepare samples for downstream experiments such as SDS-PAGE or mass spectrometry. Protein gel preparation, for example, will make your samples ready for clean gel runs, which is essential if you are performing a mass spec analysis.

Protein cleanup kits can be an effective alternative to classical protein concentration methods such as ammonium sulfate precipitation, and very useful for when you need to reach a concentration threshold for analytical experiments. Also, on-column digestion kits will aid in retrieving highly pure protein for affinity and immunoaffinity chromatography columns.

When choosing a protein cleanup kit, consider what kind of source sample you need. Also, you should always keep in mind what the requirements are for your downstream applications regarding protein yield and purity.

If your kit uses columns, be sure to check whether your target protein falls within the column cutoff value. Last but not least, don't forget the processing time. Some kits are quicker than others, so time might be something to consider if you perform this experiment routinely.

DNA / RNA Cleanup

Similarly, it is advisable to use a DNA and RNA cleanup kit before using the resultant nucleic acids for quantification, cloning or sequencing experiments. PCR purification kits will remove templates, primers, and nucleotides to give the clean, desired amplified DNA.

Furthermore, nucleic acid purification from the gel is typically used to select a precise fragment after an agarose gel run. While various gel extraction protocols exist, gel extraction kits have the necessary tools for a fast and easy nucleic acid extraction from your gels.

Our DNA Gel Cleanup Troubleshoot can help minimize any losses.

As with protein kits, product yield and purity are essential, as well as DNA size and RNA size column cutoffs. Visit our Influenza article for real-life application of Gel RNA Cleanup.

Compare RNA Cleanup Kits

With our comparison engine, you can avoid all the time and energy wasted sifting through multiple web pages from different suppliers. At ZAGENO you can clearly see kits side-by-side, with the relevant attributes for each kit neatly in line for easy selection of the best product for you.

The ZAGENO comparison does not highlight one kit to be better than the other, as the kit of choice may vary between researchers - depending on each individual's preferred attributes. The best kit is the one that meets your needs - ZAGENO allows you to make an informed decision with minimum effort.

Check out our How It Works page for a guide to using the comparison function.