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Gene Silencing Kits

Lullaby Stem siRNA Transfection Reagent

OZ Biosciences

RNAi Type
miRNA, siRNA
miRNA, siRNA
Targets
mRNA
mRNA
Organism
Human
Human
From
$ 178.00 (500 µl)
Sizes
2 (500 - 1000 µl)
Catalog IDs
LS20500, LS21000
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Gene Silencing Kits

DharmaFECT 4 Transfection Reagent

Dharmacon

RNAi Type
miRNA, siRNA
miRNA, siRNA
Targets
miRNA, siRNA
miRNA, siRNA
Organism
Animals
Animals
From
$ 99.00 (200 µl)
Sizes
5 (200 - 20000 µl)
Catalog IDs
T-2004-01, T-2004-02, ...
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Gene Silencing Kits

Accell siRNA Delivery Media

Dharmacon

RNAi Type
siRNA
siRNA
Targets
mRNA
mRNA
Organism
Animals, Human
Animals, Human
From
$ 16.00 (100 ml)
Sizes
2 (100 - 500 ml)
Catalog IDs
B-005000-100, B-005000-500
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Gene Silencing Kits

In Vivo Silencemag Trial Kit

OZ Biosciences

RNAi Type
/
/
Targets
/
/
Organism
/
/
From
$ 145.55 (1 Kit)
Sizes
1 (1 Kit)
Catalog IDs
IV-TK30240
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Gene Silencing Kits

X-tremeGENE™ siRNA Transfection Reagent

Roche Life Science

RNAi Type
siRNA
siRNA
Targets
Plasmid DNA, siRNA
Plasmid DNA, siRNA
Organism
Animals
Animals
From
$ 264.00 (1000 µl)
Sizes
2 (1000 - 5000 µl)
Catalog IDs
4476093001, 4476115001
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Gene Silencing Kits

Score 6.20

MISSION® siRNA Transfection Reagent

Sigma-Aldrich

RNAi Type
/
/
Targets
/
/
Organism
Animals, Human
Animals, Human
From
$ 57.00 (100 µl)
Sizes
2 (100 - 1000 µl)
Catalog IDs
S1452-100UL, S1452-1ML
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Gene Silencing Kits

Score 9.80

N-TER™ Nanoparticle siRNA Transfection System

Sigma-Aldrich

RNAi Type
siRNA
siRNA
Targets
mRNA
mRNA
Organism
Animals, Fungi, Human, Insects, Plants, Vertebrates, Yeast
Animals, Fungi, Human, Insects, Plants, Vertebrates, Yeast
From
$ 82.50 (120 µl)
Sizes
3 (120 - 1000 µl)
Catalog IDs
N2913-120UL, N2913-400UL, ...
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Gene Silencing Kits

ON-TARGETplus Non-targeting Pool

Dharmacon

RNAi Type
siRNA
siRNA
Targets
mRNA
mRNA
Organism
Animals, Human
Animals, Human
From
$ 228.00 (5 nmol)
Sizes
3 (5 - 50 nmol)
Catalog IDs
D-001810-10-05, D-001810-10-20, ...
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Gene Silencing Kits

Transfection Selection Kit #4

OZ Biosciences

RNAi Type
/
/
Targets
/
/
Organism
/
/
From
$ 334.75 (1 Kit)
Sizes
1 (1 Kit)
Catalog IDs
KM30400
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Gene Silencing Kits

Transfection Starting Kit #2

OZ Biosciences

RNAi Type
/
/
Targets
/
/
Organism
/
/
From
$ 545.90 (1 Kit)
Sizes
1 (1 Kit)
Catalog IDs
KC30396
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Gene Silencing Kits

Transfection Starting Kit #3

OZ Biosciences

RNAi Type
/
/
Targets
/
/
Organism
/
/
From
$ 757.05 (1 Kit)
Sizes
1 (1 Kit)
Catalog IDs
KC30496
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Gene Silencing Kits

Rmesfect Crispr Transfection Reagent

OZ Biosciences

RNAi Type
/
/
Targets
/
/
Organism
/
/
From
$ 197.82 (500 µl)
Sizes
1 (500 µl)
Catalog IDs
RMC70500
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Gene Silencing Functionality

Gene Silencing refers to a series of gene editing techniques that reduces the transcription or translation of a gene. In contrast with genetic mutations, gene silencing selectively targets the gene of interest with various silencing intensities, taking advantage of the native gene regulation.

Recently, gene silencing was recognised to be crucial in the study of autophagy.

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RNA interference (RNAi)

RNA interference (RNAi) is a widely used gene silencing technique for the regulation of gene expression. Compared to classic mutants, gene silencing techniques can be used with an inducible promoter or under a tissue- or stage-specific control. When choosing an RNAi kit, there are a few factors to consider.

Firstly, whether you use a synthesized siRNA or if you'd prefer to clone your own. The former is a faster, high-quality solution, whereas custom made synthetic siRNA is expensive. On the other hand, in vivo creation of siRNA creates an entire collection of siRNA against a target gene, which increases the chances of a successful silencing. While this is a lengthy process, there are kits that can make the process easier.

Secondly, the method of siRNA delivery in the cell. While synthesized siRNAs can be delivered directly with dedicated reagents or physical methods such as magnetic beads, it is also possible to express RNAs that will be processed in the cell to become siRNAs. This approach requires the use of specific vectors, but is advantageous by using selectable markers or time- and cell-type- specific expression.

Use our Gene Silencing Troubleshoot to fix any problems which arise.

Compare Gene Silencing Kits

With our compare function, you can avoid all the time and energy wasted sifting through multiple web pages from different suppliers. At ZAGENO you can clearly see kits side-by-side, with the relevant attributes for each kit neatly in line for easy selection of the best product for you.

Video Credits:

Video: TED-Ed/YouTube