Specifications

Variant Details
Catalog IDPAB19807-100UGSupplier Catalog IDPAB19807-100UG
Size100 µgPrice N/A
Supplier N/A Package Content AKR1C3, Rabbit, Polyclonal Antibody, Abnova™, Each: 100µg
General
AntigenAKR1C3ClonalityPolyclonal
HostRabbitReactivityHuman
ApplicationsELISA, Immunofluorescence, Immunohistochemistry, Western BlotConjugatedUnconjugated
ImmunogenA synthetic peptide corresponding to 15 amino acids at C-terminus of human AKR1C3.DilutionELISA: 1:10000-1:40000, Western Blot: 1:500-1000, IHC-P: 1:100-500, Immunofluorescence: 1:50-1:200
FormulationIn serum (2% BSA, 0.02% sodium azide)Genealdo-keto reductase family 1 member C3 (AKR1C3, Homo sapiens)
Gene ID8644 (Homo sapiens)Alternative Names & SynonymsDD3,DDX,PGFS,HAKRB,HAKRe,HA1753,HSD17B5,hluPGFS (Homo sapiens)
Storage & HandlingStore at 4°C for three months. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.

Description

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq

For research use only.