Brand
St John's Laboratory
Manufacturer
St John's Laboratory
Mfr. Catalog ID
STJ120152-25UG
Size (Packaging)
1 available
Supplier
1 available
Description
Full product descriptions are available for ZAGENO customers.
Get Started

SUPPLIER CATALOG ID

STJ120152 Copy Catalog ID

Price on Request

Join ZAGENO's Marketplace

The largest life sciences lab supply marketplace.

  • 20 MILLION+ SKUs
  • 3,500+ SUPPLIERS
  • SCIENTIFIC EXPERTS AT YOUR SERVICE
Access ZAGENO Marketplace
Specifications
Mfr. Catalog IDSTJ120152-25UG
Supplier Catalog IDSTJ120152
Size25 µg (1 x 25 µg)
Price$ 607.60
SupplierSt John's Laboratory, US
Package ContentsAnti-NMDAR1 C2 antibody (KLH)
ClonalityPolyclonal
HostRabbit
ReactivityHuman, Mouse, Rat
ApplicationsImmunohistochemistry, Western Blot
ConjugatedConjugated
Conjugate TypeKLH (Keyhole Limpet Hemocyanin)
ImmunogenSynthetic peptide corresponding to amino acid residues specific to the NR1 subunit, C2 splice variant insert conjugated to KLH.
DilutionWB 1:1000; IHC 1:1000-1:2000
FormulationLyophilized
Purification MethodThis antibody was antigen affinity purified from serum.
Gene ID24408[uid]
Alternative Names & SynonymsAnti-Glutamate Receptor Ionotropic-Nmda 1 antibody</br>Anti-Glun1 antibody</br>Anti-Glutamate Nmda Receptor Subunit Zeta-1 antibody</br>Anti-N-Methyl-D-Aspartate Receptor Subunit Nr1 antibody</br>Anti-Nmd-R1 antibody</br>Anti-Grin1 Nmdar1 antibody
UniProtKB/Swiss-Prot P35222 (CTNB1_HUMAN)
Molecular Weight120 kDa
Additional InformationThe ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA Receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimers, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002; Wenthold et al., 2003; Carroll and Zukin, 2002). There are a number of different splice variants of the NR1 subunit (Foldes et al., 1994; Zukin and Bennett, 1995). Differential splicing of three exons in the NR1 subunit generates up to eight NR1 subunit splice variants and 7 of these have been identified in cDNA libraries. These exons encode a 21 amino acid N-terminal domain (N1) and adjacent sequences in the C-terminus (C1 and C2). Splicing out the C2 cassette eliminates the first stop codon and produces a new reading frame that generates a new sequence of 22 amino acids (C2&#8242;). Considerable attention has been focused on the distribution and expression of these splice variants that may affect the functional properties and regulation of the NMDAR.
FormLyophilized
Shipping Temperature4 °C
Storage & HandlingStore at-20°C, and avoid repeated freeze-thaw cycles.