BGN, also known as biglycan, is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex. Source: Recombinant protein corresponding to human BGN, fused to His-tag at N-terminal expressed in E.coli.Molecular Weight: ~39.5kD (352aa) AA Sequence:MGSSHHHHHH SSGLVPRGSH MDEEASGADT SGVLDPDSVT PTYSAMCPFG CHCHLRVVQC SDLGLKSVPK EISPDTTLLD LQNNDISELR KDDFKGLQHL YALVLVNNKI SKIHEKAFSP LRKLQKLYIS KNHLVEIPPN LPSSLVELRI HDNRIRKVPK GVFSGLRNMN CIEMGGNPLE NSGFEPGAFD GLKLNYLRIS EAKLTGIPKD LPETLNELHL DHNKIQAIEL EDLLRYSKLY RLGLGHNQIR MIENGSLSFL PTLRELHLDN NKLARVPSGL PDLKLLQVVY LHSNNITKVG VNDFCPMGFG VKRAYYNGIS LFNNPVPYWE VQPATFRCVT DRLAIQFGNY KKStorage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
by US Biological
BGN, Recombinant, Human, aa38-368, His-Tag (Biglycan Preproprotein, DSPG1, PG-S1, PGI, SLRR1A) SKU: 137004
|Catalog ID||137004-100UG||Supplier Catalog ID||137004-100ug|
|Size||100 µg||Price||$ 460.00|
|Supplier||United States Biological Inc.||Package Content||BGN, Recombinant, Human, aa38-368, His-Tag (Biglycan Preproprotein, DSPG1, PG-S1, PGI, SLRR1A), 100ug|
|Additional Information||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 10% glycerol, 0.4M urea.||Shipping Temperature||Blue Ice|
|Storage & Handling||-20°C||Source||Recombinant, E.coli|
For research use only.