Specifications

Variant Details
Catalog IDB-CCL19-2ugSupplier Catalog IDB-CCL19-2ug
Size2 µgPrice $ 84.50
Supplier ChemoTactics, Inc. Package Content CCL19 (MIP-3β) Biotin Chemokine, 2 µg
General
Applicable Processes/ConjugatedConjugated
Purity> 97 %Molecular Weight11.219 kDa
SolubilitySterile waterShipping ConditionRoom temperature
Shipping Temperature20 °CStorage & Handling-20 °C
Shelf Life12 monthsResearch Topics/

Description

Macrophage inflammatory protein-3-beta (MIP3β) (CCL19), also known as EBI1 ligand chemokine (ELC), directs chemotaxis of dendritic cells, and certain B- and T- lymphocytes, but not monocytes or granulocytes. It is constituitively expressed in thymus and lymph nodes and binds specifically to target cells expressing the receptor CCR7. Being a homeostatic chemokine, its primary physiological role is considered to be in the normal recirculation and homing of lymphocyte. However, MIP-3β could also be proinflammatory, and is implicated in the post-HIV infection responses.

For research use only.