Monocyte chemoattractant protein-1 (MCP-1) (CCL2) is produced by many cell types at sites of inflammation. It regulates chemotaxis and transendothielial migration of monocytes, as well as memory T cells and natural killer cells by interacting with their membrane surface receptor CCR2. MCP-1 has also been implicated in a number of disease states, such as rheumatoid arthritis, psoriasis, atherosclerosis, autoimmune diseases, tumor progression, and HIV infection. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It binds to chemokine receptors CCR2 and CCR4.
6.72 Scientific score
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|Catalog ID||CCL2-2ug||Supplier Catalog ID||CCL2-2ug|
|Size||2 µg||Price||$ 38.35|
|Supplier||ChemoTactics, Inc.||Package Content||CCL2 (MCP-1) Chemokine, 2 µg|
|Conjugated||Unconjugated||Purity||> 97 %|
|Molecular Weight||8.662 kDa||Solubility||Sterile water|
|Shipping Condition||Room temperature||Shipping Temperature||20 °C|
|Storage & Handling||-20 °C||Shelf Life||12 months|
For research use only.