Specifications

Variant Details
Catalog IDCCL2-1mgSupplier Catalog IDCCL2-1mg
Size1 mgPrice $ 1,381.25
Supplier ChemoTactics, Inc. Package Content CCL2 (MCP-1) Chemokine, 1 mg
General
ConjugatedUnconjugatedPurity> 97 %
Molecular Weight8.662 kDaSolubilitySterile water
Shipping ConditionRoom temperatureShipping Temperature20 °C
Storage & Handling-20 °CShelf Life12 months

Description

Monocyte chemoattractant protein-1 (MCP-1) (CCL2) is produced by many cell types at sites of inflammation. It regulates chemotaxis and transendothielial migration of monocytes, as well as memory T cells and natural killer cells by interacting with their membrane surface receptor CCR2. MCP-1 has also been implicated in a number of disease states, such as rheumatoid arthritis, psoriasis, atherosclerosis, autoimmune diseases, tumor progression, and HIV infection. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It binds to chemokine receptors CCR2 and CCR4.

For research use only.