Variant Details
Catalog IDCCL4-100ugSupplier Catalog IDCCL4-100ug
Size100 µgPrice $ 304.20
Supplier ChemoTactics, Inc. Package Content CCL4 (MIP-1β) Chemokine, 100 µg
Purity> 97 %Molecular Weight7.818 kDa
SolubilitySterile waterShipping Temperature20 °C
Storage & Handling-20 °CShelf Life12 months


Monokine with inflammatory and chemokinetic properties binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

For research use only.