Specifications

Variant Details
Catalog IDbs-7549R-Cy3-100ULSupplier Catalog IDbs-7549R-Cy3
Size100 µlPrice $ 402.00
Supplier Bioss Inc. Package Content GAS 6 Polyclonal Antibody, Cy3 Conjugated, 100ul
General
AntigenGAS 6ClonalityPolyclonal
HostRabbitReactivityHuman, Mouse, Rat
ApplicationsImmunofluorescence, ImmunohistochemistryConjugatedConjugated
Conjugate TypeCy (Cyanine)Specific ConjugateCy3
IsotypeIgGImmunogenKLH conjugated synthetic peptide derived from human GAS 6 (560-610/721)
Concentration1µg/µlDilutionIF(IHC-P)(1:50-200)
Purification MethodPurified by Protein A.GeneGAS 6
Gene ID2621 (Homo sapiens)Alternative Names & SynonymsAXSF; AXLLG; Growth arrest-specific protein 6; GAS-6; AXL receptor tyrosine kinase ligand; GAS6
UniProtKBQ14393Storage & HandlingStore at 4°C for 12 months
Storage BufferAqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide

Description

Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

For research use only.

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Validation