Specifications

Variant Details
Catalog IDbs-0837R-HRP-100ULSupplier Catalog IDbs-0837R-HRP
Size100 µlPrice $ 402.00
Supplier Bioss Inc. Package Content GLUR/glutathione reductase Antibody, HRP Conjugated, 100ul
General
AntigenGLUR/glutathione reductaseClonalityPolyclonal
HostRabbitReactivityHuman, Mouse, Rat
ApplicationsImmunohistochemistry, Western BlotConjugatedConjugated
Conjugate TypeHRP (Horseradish Peroxidase)IsotypeIgG
ImmunogenKLH conjugated synthetic peptide derived from human GSRConcentration1µg/µl
DilutionWB(1:300-1000), IHC-P(1:200-400)Purification MethodPurified by Protein A.
GeneGLUR/glutathione reductaseGene ID2890 (Homo sapiens)
Alternative Names & Synonymsglutathione reductase; GLUR; Glutathione reductase mitochondrial; GR; Gr1; GRase; GRD 1; GRD1; GSR; MGC78522.Storage & HandlingStore at 4°C for 12 months
Storage BufferAqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin

Description

Glutathione reductase (GR) is a member of pyridine nucleotide- disulfideoxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG): GSSG + NADPH + H+?2GSH + NADP+. In mosteukaryotic cells, GR maintains the ratio of [GSH]/[GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.

For research use only.

Resources

Protocol

Article

Protocol

Safety

Brochure

Handbook

Publication

Validation