Specifications

Variant Details
Catalog ID351265-250UGSupplier Catalog ID351265
Size250 µgPrice $ 1,097.00
Supplier United States Biological Inc. Package Content Growth hormone Receptor, Recombinant, Rat, aa19-265, His-Tag (GHR, GHR/BP), 250µg
General
Purity~95% (SDS-PAGE)Molecular Weight29.4
Shipping ConditionWet iceStorage & Handling-20°C/-70°C

Description

GHR, also known as growth hormone receptor, is a member of the cytokine receptor superfamily. GHR forms a complex with a tyrosine kinase, suggesting involvement of a ligand-activated tyrosine kinase in intracellular signaling by growth hormone (GH). Binding of GH to its receptor results in dimerization of the receptor, phosphorylation of the tyrosine kinase JAK2 and of the receptor, followed by a cascade of protein phosphorylations.

Source:
Recombinant protein corresponding to aa19-265 from rat GHR, fused to His-tag at C-terminal expressed in Insect cell.

Molecular Weight:
~29.4kD (255aa)

AA Sequence:
FPGSGATPAT LGKASPVLQR INPSLRESSS GKPRFTKCRS PELETFSCYW TEGDDHNLKV PGSIQLYYAR RIAHEWTPEW KECPDYVSAG ANSCYFNSSY TSIWIPYCIK LTTNGDLLKE KCFTVDEIVQ PDPPIGLNWT LLNISLPGIR GDIQVSWQPP PSADVLKGWI ILEYEIQYKE VNETKWKTMS PIWSTSVPLY SLRLDKEHEV RVRSRQRSFE KYSEFSEVLR VTFPQMDTLA ACEEDFRLEH HHHHH

Endotoxin: ~1EU/1ug (LAL)

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

For research use only.