Specifications

Variant Details
Catalog ID216973-1000UGSupplier Catalog ID216973
Size1 mgPrice $ 499.00
Supplier United States Biological Inc. Package Content Hamster Anti-Mouse TCR mAb SKU:216973, 1mg
General
ClonalityMonoclonalHostHamster
ReactivityMouseCross ReactivityMonkey
ApplicationsFlow cytometryClone No.14L876
IsotypeIgGImmunogenMouse thymus
Purification MethodPurified by Protein A/G affinity chromatography.GeneTCR
FormLyophilizedShipping TemperatureBlue Ice
Storage & Handling-20°CStorage BufferPBS. No preservative added.
PurityAffinity Purified

Description

T cell receptor (TCR) is a heterodimer consisting of an a and a b chain (TCR a/b) or a g and a d chain (TCR g/d). TCR g/d belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The g/d TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most g/d T cells are CD4-/CD8-, some are CD8+. T cells expressing the g/d TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that g/d T cells also play a principal role in antigen presentation.

Applications:
Suitable for use in Flow Cytometry, activation, and depletion. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Endotoxin: <0.002EU/ug

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

For research use only.