Specifications

Variant Details
Catalog IDPAB8747-100UGSupplier Catalog IDPAB8747-100UG
Size100 µgPrice N/A
Supplier N/A Package Content HDAC1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™, SKU: PAB8747, Each: 100µg
General
AntigenHDAC1ClonalityPolyclonal
HostRabbitReactivityHuman, Mouse, Rat
ApplicationsImmunohistochemistry, Immunoprecipitation, Western BlotConjugatedUnconjugated
ImmunogenA synthetic peptide corresponding to C-terminus of human HDAC1.DilutionWestern Blot: 0.5-4 μg/ml, Immunoprecipitation: 10-20 μg/ml, IHC-P: 10-20 μg/ml
FormulationIn PBS, pH 7.2 (30% glycerol, 0.5mg/mL BSA, 0.01% thimerosal)Genehistone deacetylase 1 (HDAC1, Homo sapiens)
Gene ID3065 (Homo sapiens)Alternative Names & SynonymsHD1,RPD3,KDAC1,GON-10,RPD3L1 (Homo sapiens)
Storage & HandlingStore at -20°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.

Description

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq

For research use only.