Specifications

Variant Details
Catalog IDZ02834-10UGSupplier Catalog IDZ02834-10UG
Size10 µgPrice N/A
Supplier N/A Package Content MCP-2/CCL8, Human
General
Expression SystemE. coliProtein TypeChemokine
FormulationLyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 100 mM NaCl.Purity> 96 % by SDS-PAGE and HPLC analyses.
Endotoxin<1 EU/μg of rHuMCP-2/CCL8 as determined by LAL method.Molecular WeightApproximately 8.9 kDa, a single non-glycosylated polypeptide chain containing 76 amino acids.
Storage & Handling2-8 °C, but best kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, store at 2-8 °C for 1 week. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C. Avoid repeated freeze/thaw cycles.

Description

MCP-2 and MCP-3 are two monocyte chemotactic proteins produced by human MG-63 osteosarcoma cells. Both MCP-2 and MCP-3 are members of the CC family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP-1.MCP-3 also shares 58% amino acid identity with MCP-2.Similarly to other CC chemokines, all three MCP proteins are monocyte chemoattractants. In addition,the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.

For research use only.

Resources

Safety

MSDS : 15368_20120105034724.PDF

Brochure

Datasheet : Z02834-10_2016-08-02.pdf

Article

Protocol

Safety

MSDS : 15368_20120105034724.PDF

Brochure

Datasheet : Z02834-10_2016-08-02.pdf

Handbook

Publication

Validation