Variant Details
Catalog ID130844-100UGSupplier Catalog ID130844
Size100 µgPrice $ 539.00
Supplier United States Biological Inc. Package Content Mouse Anti-Human PAK2 mAb SKU:130844, 100ug
ReactivityHumanCross ReactivityHuman
ApplicationsELISA, Western BlotClone No.1E1
IsotypeIgGImmunogenPartial recombinant corresponding to aa131-230 from human PAK2 (NP_002568) with GST tag
Purification MethodPurified by Protein A affinity chromatography.GenePAK2
UniProtKBQ13177GenBank Accession No.NM_002577
FormLiquidShipping TemperatureBlue Ice
Storage & Handling-20°CStorage BufferPBS, pH 7.2.
PurityAffinity Purified


The PAK (p21-activated kinase) family of serine/threonine kinases plays an important role in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, etc. Binding of Rac/cdc42 to the CRIB (or PBD) domain at the N-terminal region of PAK causes autophosphorylation and conformational change of PAK. Phosphorylation of Ser21 of PAK1 or Ser20 of PAK2 regulates its binding with the adaptor protein Nck.

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

AA Sequence:

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

For research use only.