Specifications

Variant Details
Catalog ID216892-100UGSupplier Catalog ID216892
Size100 µgPrice $ 499.00
Supplier United States Biological Inc. Package Content Mouse Anti-Human Platelet Derived Growth Factor C (PDGF-C) mAb SKU:216892, 100ug
General
ClonalityMonoclonalHostMouse
ReactivityHumanCross ReactivityHuman
ApplicationsNeutralizationClone No.14L796
IsotypeIgGImmunogenRecombinant protein corresponding to human PDGF-C.
Purification MethodPurified by Protein G affinity chromatography.GenePlatelet Derived Growth Factor C (PDGF-C)
FormLyophilizedShipping TemperatureBlue Ice
Storage & Handling-20°CStorage BufferPBS.
PurityAffinity Purified

Description

The term ‘PDGF’ refers to a family of disulphide bondlinked dimeric isoforms that act as autocrine and paracrine growth factors and are produced by a variety of cell types other than platelets. They act as potent mitogens for almost all mesenchymally-derived cells. Aberrant expression is involved in certain cancers, fibroproliferative disorders and atherosclerosis. The protein also contributes to wound healing and neural regeneration. There are four members of the PDGF family – PDGF A, PDGF B, PDGF C and PDGF D. Two distinct types of PDGF-A exist – a short form that is soluble and a long form that is retained by the extracellular matrix.

Applications:
Suitable for use in Neutralization. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

For research use only.