Specifications

Variant Details
Catalog ID137136-100UGSupplier Catalog ID137136
Size100 µgPrice $ 460.00
Supplier United States Biological Inc. Package Content NDUFS6, Recombinant, Human, 28-124aa, His-Tag (NADH Dehydrogenase [Ubiquinone] Iron-sulfur Protein 6, CI-13Ka, CI-13kD-A, CI13KDA), 100ug
General
SourceRecombinant, E.coliAdditional InformationSupplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.15M NaCl, 30% glycerol, 1mM DTT.
Shipping TemperatureBlue IceStorage & Handling-20°C

Description

NDUFS6 is a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit is one of seven subunits in the iron-sulfur protein fraction. Mutations cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders. Source: Recombinant protein corresponding to human NDUFS6, fused to His-tag at N-terminal expressed in E.coli.Molecular Weight: ~13.2kD (120aa) (MALDI-TOF) AA Sequence:MGSSHHHHHH SSGLVPRGSH MGSFGVRVSP TGEKVTHTGQ VYDDKDYRRI RFVGRQKEVN ENFAIDLIAE QPVSEVETRV IACDGGGGAL GHPKVYINLD KETKTGTCGY CGLQFRQHHHStorage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

For research use only.