Variant Details
Catalog IDABC-KC1417-100UGSupplier Catalog IDABC-KC1417
Size100 µgPrice $ 950.00
Supplier AcceGen Biotechnology, US Package Content 1 vial of knockout cell lysate and 1 vial of parental cell lysate


This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012]

For research use only.