Specifications

Variant Details
Catalog ID10720Supplier Catalog ID10720
Size500 µgPrice $ 235.00
Supplier Cepham Life Sciences, Inc. Package Content Rabbit anti-Human IgG Fc fragment polyclonal Antibody, FITC conjugated
General
ClonalityPolyclonalHostRabbit
ReactivityHumanConjugatedConjugated
Shipping Temperature4 °C

Description

Conjugate FITC Form Liquid Immunogen Human IgG Fc fragment Host Rabbit Product Description Caprylic Acid Ammonium Sulfate Precipitation purified Specificity The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. InIgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibodys two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2–4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and α-2,6 linked sialic acid residues. Application ELISA.Not yet tested in other applications. Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

For research use only.