Runt-related transcription factor 2 (RUNX2) is a member of the RUNX family of transcription factors. RUNX2 has an Runt domain and can bind DNA both as a monomer or as a subunit of a heterodimeric complex. RUNX2 has a role in osteoblastic differentiation and skeletal morphogenesis and is essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. RUNX2 is specifically expressed in the nucleus of osteoblasts. 3 isoforms are produced by alternative splicing.Applications: Suitable for use in Western Blot. Other applications not tested.Recommended Dilution: Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
|Catalog ID||215457-100UG||Supplier Catalog ID||215457|
|Size||100 µg||Price||$ 569.00|
|Supplier||United States Biological Inc.||Package Content||Rabbit Anti-human RUNX2 polyclonal antibody SKU:215457, 100 µg|
|Reactivity||Human||Cross Reactivity||Human, Rat|
|Isotype||IgG||Immunogen||Synthetic peptide corresponding to aa244-258 from human Runt-related Transcription Factor 2, coupled to carrier protein BSA.|
|Specificity||Recognizes human Runt-related Transcription Factor 2.||Dilution||Western Blot: 0.1-0.5ug/ml Optimal dilutions to be determined by the researcher.|
|Purification Method||Purified by immunoaffinity chromatography.||Gene||RUNX2|
|Shipping Temperature||Blue Ice||Storage & Handling||-20°C|
For research use only.