SGCD is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. The mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed. In melanocytic cells SGCD gene expression may be regulated by MITF. Source: Recombinant protein corresponding to human SGCD, fused to His-tag at N-terminal expressed in E.coli.Molecular Weight: ~28kD (257aa)AA Sequence:MGSSHHHHHH SSGLVPRGSH RSHMKVMNFT IDGMGNLRIT EKGLKLEGDS EFLQPLYAKE IQSRPGNALY FKSARNVTVN ILNDQTKVLT QLITGPKAVE AYGKKFEVKT VSGKLLFSAD NNEVVVGAER LRVLGAEGTV FPKSIETPNV RADPFKELRL ESPTRSLVME APKGVEINAE AGNMEATCRT ELRLESKDGE IKLDAAKIRL PRLPHGSYTP TGTRQKVFEI CVCANGRLFL SQAGAGSTCQ INTSVCLStorage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
by US Biological
SGCD, Recombinant, Human, aa57-289, His-Tag (Delta-sarcoglycan, 35DAG, CMD1L, DAGD, SG-delta, SGCDP, SGD) SKU: 137207
|Catalog ID||137207-100UG||Supplier Catalog ID||137207-100ug|
|Size||100 µg||Price||$ 460.00|
|Supplier||United States Biological Inc.||Package Content||SGCD, Recombinant, Human, aa57-289, His-Tag (Delta-sarcoglycan, 35DAG, CMD1L, DAGD, SG-delta, SGCDP, SGD), 100ug|
|Additional Information||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.4M urea, 10% glycerol.||Shipping Temperature||Blue Ice|
|Storage & Handling||-20°C||Source||Recombinant, E.coli|
For research use only.