Specifications

Variant Details
Catalog IDbs-9635R-FITC-100ULSupplier Catalog IDbs-9635R-FITC-100UL
Size100 µlPrice N/A
Supplier N/A Package Content SLC39A11 Polyclonal Antibody, FITC Conjugated, 100ul
General
AntigenSLC39A11ClonalityPolyclonal
HostRabbitReactivityHuman, Mouse, Rat
ApplicationsImmunofluorescence, ImmunohistochemistryConjugatedConjugated
Conjugate TypeFITC (Fluorescein isothiocyanate)IsotypeIgG
ImmunogenKLH conjugated synthetic peptide derived from human SLC39A11Concentration1µg/µl
DilutionIF(IHC-P)(1:50-200)Purification MethodPurified by Protein A.
GeneSLC39A11Gene ID201266 (Homo sapiens)
Alternative Names & SynonymsC17orf26; S39AB_HUMAN; SLC39A11; Solute carrier family 39 metal ion transporter member 11; Solute carrier family 39 member 11; Zinc transporter ZIP11; ZIP-11; ZIP11; Zrt and Irt like protein 11; Zrt- and Irt-like protein 11.Storage & HandlingStore at 4°C for 12 months
Storage BufferAqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide

Description

Zinc is an essential cofactor that is involved in cell growth and development, as well as in protein, nucleic acid and lipid metabolism. The transport of zinc across the cell membrane is crucial for correct enzyme and overall cell function. SLC39A11 (solute carrier family 39 (metal ion transporter), member 11), also known as ZIP11 (Zrt- and Irt-like protein 11), is a 342 amino acid multi-pass membrane protein belonging to the ZIP transporter family. Expressed as multiple alternatively spliced isoforms, SLC39A11 acts as a zinc-influx transporter and is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

For research use only.

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