UPK3A is a member of the uroplakin-3 family. Uroplakins (UP) which are transmembrane proteins are important components of the urothelium that pass the lipid bilayer once (UPII, UPIIIa, and UPIIIb) or four times (UPIa and UPIb; both members of the "tetraspanin" family). All hold great luminal/extracellular domains, but only UPIIIa and UPIIIb have significant cytoplasmic shares in their C-termini. UPK3A is an extremely specific and moderately sensitive immunohistochemical marker for primary and metastatic urothelial carcinomas. Alterations in this gene are related to renal adysplasia.Source:Recombinant protein corresponding to human UPK3A, expressed in E. coli. Molecular Weight: ~23.1kDAA Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMVNLQP QLASVTFATN NPTLTTVALE KPLCMFDSKE ALTGTHEVYL YVLVDSAISR NASVQDSTNT PLGSTFLQTE GGRTGPYKAV AFDLIPCSDL PSLDAIGDVS KASQILNAYL VRVGANGTCL WDPNFQGLCN PPLSAATEYR FKYVLVNMST GLVEDQTLWS DPIRTNQLTP YSTIDTWPGR RSGGStorage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
by US Biological
UPK3A, Recombinant, Human (Uroplakin 3A, UPK3, UPIII, Uroplakin III, UP3A) SKU: 220407
|Catalog ID||220407-10UG||Supplier Catalog ID||220407-10ug|
|Size||10 µg||Price||$ 462.00|
|Supplier||United States Biological Inc.||Package Content||UPK3A, Recombinant, Human (Uroplakin 3A, UPK3, UPIII, Uroplakin III, UP3A), 10ug|
|Source||Recombinant, E. coli||Purity||~90% (SDS-PAGE)|
|Additional Information||Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 150mM NaCl, 2mM DTT, 20% glycerol.||Shipping Temperature||RT|
|Storage & Handling||-20°C|
For research use only.